Description
Product Characteristics: VPS 24 antibody, VPS24 antibody, CGI 149 antibody, CGI149 protein antibody, Charged multivesicular body protein 3 antibody, CHMP3 antibody, CHMP3_HUMAN antibody, Chromatin modifying protein 3 antibody, Chromatin-modifying protein 3 antibody, HGNC:29865 antibody, hVps24 antibody, NEDF antibody, Neuroendocrine differentiation factor antibody, Vacuolar protein sorting 24 (yeast) antibody, Vacuolar protein sorting 24 homolog (S. cerevisiae) antibody, Vacuolar protein sorting associated protein 24 antibody, Vacuolar protein sorting-associated protein 24 antibody, vps24 antibody
Target Information: This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. [provided by RefSeq, Nov 2010]